The first Osteonet Workshop

On April 4th and 5th, the LINKS Foundation in Turin hosted the inaugural OsteoNET workshop, a groundbreaking event that brought together experts and enthusiasts from various disciplines to delve into the latest advancements in bone health research. The workshop featured five engaging round table discussions, three on the first day and two on the second, providing a platform for in-depth exploration and collaboration.

Adjacent to the main conference room, an inspiring poster exhibition showcased the work of invited guests, offering a visual journey through their research findings and acknowledgments. Held during coffee breaks, the exhibition served as a catalyst for networking, fostering connections and discussions among participants.

The round table discussions featured a diverse panel of speakers, including OsteoNET partners and external experts specializing in bone tissue engineering, 3D printing techniques, biomaterials, AI, and biomedical modeling biomaterials applied to the biomedical sector. Moreover, the workshop has been conceived to give an overview of the Space-related issues that astronauts face during spaceflight. In fact, there are phenotypic similarities of some conditions during Spaceflight such as bone loss mass and osteopenia, with some metabolic disorder on Earth, for example osteoporosis. The biological mechanisms at the basis of many of these diseases are not yet fully understood, so the microgravity effects on the same tissue could be used as an accelerated model for a deeper understanding of the mechanisms involved. 

The workshop accommodated both in-person and online participation, attracting approximately 90 attendees keen to contribute to the discourse and exchange ideas.

On April 4th, the first round table, moderated by Dr. Elisa Scatena from the Hypatia Research Consortium, examined the potential of space research in advancing bone tissue engineering. Eng. Costantino Del Gaudio (Italian Space Agency), Eng. Armando Ciampolini (E. Amaldi Foundation), and Dr. Rosa Sapone (ALTEC) shared valuable insights into this fascinating intersection of space science and biomedicine.

(The first round table discussion: Exploring the pathophysiology of bone: the gap between bone disease and healthy and the opportunities of the space challenge)

The second round table, moderated by Dr. Kostantinos Theofilatos from INSYBIO, delved into the biological aspects and regenerative processes of musculoskeletal tissue. Prof. Lihi Adler-Abramovich (Tel Aviv University), Dr. Federico Davide Costanti Mussano (University of Turin), Dr. Bartosz Kempisty (Wroclaw Medical University), and Dr. Giacomo Di Benedetto (7HC) engaged in a lively discussion on this critical topic.

(The second round table discussion: Musculoskeletal tissues: biological aspects and regenerative process)

The third round table, moderated by Dr. Giuseppe Falvo D’Urso Labate from CELLEX, focused on the uses of biomaterials and tools for tissue engineering, both on Earth and in space. Prof. Cesare Gargioli (University of Tor Vergata), Dr. Lana Van Damme (University of Ghent), Prof. Luca Ciardelli (Polytechnic of Turin), and Dr. Chiara Liverani (Istituto Romagnolo per lo Studio dei Tumori “Dino Amadori”) shared valuable insights into this fascinating area of research, with Dr. Lana Van Damme participating online.

Throughout the event, OsteoNET partners and external stakeholders showcased their posters, sparking discussions and collaborations during coffee breaks.

On April 5th, the session commenced with a round table moderated by Prof. Diana Massai (Polytechnic of Turin), focusing on the development of bioreactors and devices for regenerative medicine. Eng. Giuseppe Falvo D’Urso Labate (CELLEX), Dr. Stefano Gabetti (Polytechnic of Turin), and Prof. Andrea Cochis (University of Eastern Piedmont) led a stimulating discussion on the synergy between engineering and biology in this pioneering field.

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